AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria

Phenylketonuria (PKU) due to recessively inherited phenylalanine hydroxylase (PAH) deficiency results in hyperphenylalaninemia, which is toxic to the central nervous system.Restriction of dietary phenylalanine intake remains the standard of PKU care and prevents the major neurologic manifestations of the disease, yet shortcomings of dietary therapy

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Evaluation of unique identifiers used for citation linking [version 1; referees: 1 approved, 2 approved with reservations]

Unique identifiers (UID) are seen as an effective tool to create links between identical publications in databases or identify duplicates in a database.The purpose of the present study is to investigate how well UIDs work for citation linking.We have two objectives: Explore the coverage, precision, and characteristics of publications matched versus

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